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Male mice heterozygous for Cre Recombinase under the control of a smooth muscle 22 α [27] promoter were mated to female mice homozygous for a floxed AR [7]; all mice are maintained on a C57BL6 background.
Currently, Ts65Dn mice are maintained on a genetic background that leads to blindness in about 25% of their offspring, because it segregates for the retinal degeneration 1 (Pde6brd1) mutation of C3H/HeSnJ.
This chapter provides an overview of the salient features pertaining to the design as well as the engineering features integrated into facilities in which mice are maintained and used; macro and micro environmental conditions and monitoring; operational considerations, caging systems, and equipment employed; and the materials routinely used.
These mice are maintained as hemizygotes and transgenics were identified by examining tail-clips for EGFP expression.
However, due to infertility of Scarb1−/− females and poor breeding on the B6 background, mice are maintained on mixed B6:129 backgrounds.
Results clearly suggest that learning and memory abilities are not altered when the mHtr4 gene encoding 5-HTR4 is disrupted, as far as the mutant mice are maintained in baseline conditions.
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All mice were maintained in specific pathogen-free housing.
ICR mice were maintained in the animal facility of National Yang-Ming UNational Yang-Ming
All mice were maintained on the C57BL/6 background.
All mice were maintained on a C57BL/6 background.
All mice were maintained in the specific pathogen free (SPF) facility of the Yonsei Laboratory Animal Research Center.
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