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In conclusion, the present study has demonstrated that different DC subsets from BCG-infected mice are different in capacity to generate protective immunity.
As already indicated for classical eyeblink conditioning, it is possible that mice are different in this respect to other species of mammals.
These observations suggest that, although GHS-R is a biologically relevant ghrelin receptor that regulates GH and food intake, ghrelin and GHS-R also may have independent noncanonical functions, so that the phenotypes of Ghrl-/ and Ghsr-/ mice are different.
The protein levels of mutant SOD1 in these mice are different: SOD1G93A, SOD1G37R, SOD1G85R and SOD1G127X mice express 17-, 5-, 0.9- and 0.45-fold human mutant SOD1 of mouse wild type SOD1, respectively [20].
In support with this notion, the phenotypes of Mll1 and Mll2 knockout mice are different in adult tissues.
Moreover, the types of tumor developed in TAp73-/ mice are different from those displayed by p53-/ knockout mice.
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As expected the body weight of male and female mice was different and there was a minor but statistically significant difference in baseline albuminuria (Figure 1A).
At 72 hours, the increase in inflammatory cells seen histologically in the airways of Nlrc4−/− mice is different from the bronchoalveolar lavage data that has no difference.
The behavioral outcomes shown in A30 mice were different from those of S30 mice, despite equivalent sweetness of the aspartame solution to that of the sucrose solution.
Interestingly, the TREome landscapes of C3H/HeJ (toll-like receptor-4 [TLR4] mutant) inbred mice were different from its control C3H/HeOuJ (TLR4 wild-type) strain.
Even the behaviors of the treated mice were different.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com