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This appearance is similar to that shown by Bachman and colleagues for β less AR triple knockout mice, although the authors of this paper state that the BAT from β1-β3 double knockout mice appears normal [50].
Embryonic development of Fhod3 −/− mice appears normal up to E8.5.
The skin of FABP5 knockout mice appears normal at the gross and histological level, but the water-barrier function of the epidermis is altered in these mice.
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In all cases, the histological appearance of non-lymphoid tissues of Rac1N/Rac3KO mice appeared normal (Supporting Information Fig. 6B).
Heterozygous (CD98hcΔ/+) mice appeared normal in terms of weight, growth, fertility, and macroscopic appearance.
Slit lamp examination revealed that slc4a11−/− mice have hazy corneas (the cloudy appearance is indicated by arrows), indicating corneal oedema, whereas corneas of WT mice appeared normal and translucent (Fig. 5A).
The mice appeared normal and did not suffer any side-effects that would make such a treatment unthinkable for humans.
The mice appeared normal and did not suffer any side effects that would make such a treatment impossible for use on humans.
SV2A is an essential protein as homozygous SV2A knockout mice appear normal at birth but fail to grow, experience severe seizures and die by 3 weeks.
He points out that many cloned mice appear normal in youth but "die much earlier than controls with major problems in multiple organs".
These mice appeared normal and exhibited normal motor function for about 6 weeks, but then developed a progressive neurological disease that includes many features of RTT: tremors, motor impairments, hypoactivity, increased anxiety-related behavior, seizures, kyphosis, and stereotypic forelimb motions.
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