Sentence examples for mice and support from inspiring English sources

In summary, our data show substantial differences among AAV serotypes in transduction of human and mouse hepatocytes, are the first to report on AAV5 in humanized mice, and support the use of AAV3-based vectors for human liver gene transfer.

These data now provide a mechanistic framework for understanding the forebrain defects in oto mice, and support a role for Oto-mediated Wnt regulation during early brain development.

Our observations identify a novel mutually positive regulatory feedback loop between IFNs and ERα in immune cells in mice and support the idea that activation of this regulatory loop contributes to sex bias in SLE.

In conclusion, the reduced performance levels in the spatial navigational task provide evidence about the role of Dyrk1A in spatial learning in mice and support a role for Dyrk1A in the hippocampally-mediated interaction between stress and cognitive performance.

Our data demonstrate a requirement for Jag1/Notch2-mediated signaling in bile duct formation in mice, and support a model in which bile duct paucity in Notch pathway loss of function mutant mice results from defects in bile duct morphogenesis rather than cell fate specification.

Both findings are in full agreement with our recent findings in APOE*3-Leiden.CETP mice and support the validity of these mice as a model for human-like lipoprotein metabolism.

As described in the introduction, the knockin of C/EBPβ into the C/EBPα locus rescues the lethality of C/EBPα−/− mice and supports the notion of functional redundancies between these family members [27], [43].

For instance, colonization with Clostridia clusters XIVa and IV normalizes the enlarged cecum found in germ-free mice and supports epithelial growth and turnover.

This is the first report of the successful treatment of SCC tumours with ingenol mebutate gel in wild-type mice, and supports the view that ingenol mebutate induces primary necrosis and activates the immune system.

This would explain the significantly reduced osteogenic response in male Lrp5 −/− mice and supports the notion that the canonical Wnt signalling has a role in bone cells' response to mechanical loading.

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