Sentence examples for mice and highlight from inspiring English sources

Taken together, these findings illustrate divergent actions of GLP-1R agonists on atherosclerosis progression and accumulation of ectopic lipid in ApoE mice and highlight the importance of indirect GLP-1R actions for the control of hepatic lipid accumulation.

These studies indicate that the increased urinary excretion of phosphate and uric acid are specific to NHERF-1 null mice and highlight the fact that predictions about the role of adaptor proteins such as the NHERF proteins obtained from studies of model cell systems must be confirmed in whole animals.

Our results illustrate the differences of XCI mechanism between humans and mice, and highlight the importance of addressing the issue of imprinted XCI in other species in order to understand the evolution of dosage compensation in placental mammals.

Our studies suggest a role for Nocturnin in the white adipose tissue's response to fasting in restricted fed mice, and highlight the usefulness of Nocturnin and white adipose tissue as tools with which to investigate the intersection of circadian timing and metabolism.

These results indicate a common fate for these two proteins in Y682G mice and highlight the possibility of a consistent interplay in their signaling and activities.

Our findings suggest that mTOR signaling plays a key role in mediating bone loss in Sf mice and highlight the significance of M-CSF/mTOR/PI3K axis in autoimmune-mediated osteolytic diseases.

This review summarizes progress towards understanding the broad spectrum of immune responsiveness to the blood stages of the malaria parasite during experimental infections in mice and highlights how examination of murine malarias sheds light on the factors involved in the modulation of vaccine-potentiated immunity.

Finally, we evaluated the efficacy of CY in IFN-γ/perforin double knock-out mice and found that combined deficiency of IFN-γ and perforin completely abrogated the CY-induced anti-tumor effects (9/9 mice, two experiments), consistent with the results from the IFN-γ-knock-out mice and highlighting the key role of this effector molecule (Figure 5C).

Given the similarity between these two models, these data support the concept that cyclin D1b induction is not sufficient to restore the growth retardation phenotype observed in Ccnd1−/− mice and highlights the functional differences between the two cyclin D1 isoforms.

The augmented late gestational enlargement of intraplacental arteries, an apparently blunted angiogenic response by capillaries, elevated labyrinth cell death rates (20), and reduced fetal weight gain relative to CD1 mice all suggest abnormal placental development in late gestation in B6 mice and highlights an important role for genetics.

In this article, we present an updated analysis of the homeobox gene containing regions in human and mouse and highlight the similarities and differences of architecture within each genome and give insights into their evolution.