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Such homeostatic maturation occurs continuously in germ-free mice and does not require TLR signals (Wilson et al., 2008).
oAC protects against ECM in mice, and does not interfere with the pharmacokinetics of parenteral artesunate.
The elevated IOP occurs spontaneously in these genetically manipulated mice and does not require the ocular manipulation necessary in induced models.
This approach is based on the direct manipulation of newborn mice and does not implicate complex surgical intervention on the pregnant female as in the case of in utero electroporation [2].
Although a hybridization method is developed for globin elimination from total RNA preparations, such method is dedicated for humans, rats, and mice, and does not guarantee its validity for pigs.
This is not due to increased locomotor activity since lithium reduces open field activity in Fmr1 knockout mice and does not alter open field activity of wild-type mice [20], [21].
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Ces1d protein abundance did not increase by clofibrate administration to wild-type C57BL/6 mice and did not decrease in PPARα deficient mice (Dolinsky et al., 2003).
At baseline, Nlrp3 KO were indistinguishable from WT mice and did not differ in body, liver, spleen, or skeletal muscle weights normalized to tibia length (Additional file 3A C).
It was found that compound 12 resulted in 97.4% reduction in fungal load in mice and did not show any profound proliferative effect at lower dose (0.001 mg/ml).
We did ensure that intraperitoneal Endolipide had no deleterious effect on mice and did not protect mice from deadly plague.
Remarkably, β-catenin levels were constitutively low in doubleridge mice and did not change in response to stress (Figure 3B).
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