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We used global microarray analysis to study gene expression in the liver and duodenum of Hfe−/− mice and carbonyl iron loaded mice, and comparing it with that of wild-type mice fed a standard diet.
By simultaneously studying miRNA and mRNA expression profiles in the frontal cortex of ethanol-treated mice and comparing these with similar studies conducted in brains of human alcoholics, we provide evidence that alcohol drinking induces extensive activation of miRNA expression.
We assessed the progressive nature of myelin degradation in TgPAC-Notch3R169C mice, by analyzing the cerebral WM of younger mice and comparing the results obtained with those for 20-month-old mice.
Next, we tested whether D-WAT can be used for targeting WAPs in vivo by administering peptide into mice and comparing their tissues with tissues from sham-treated animals.
We addressed these questions by 1) breeding the Q344ter-expressing mice into the endogenous rhodopsin (rho)+/− and rho−/− backgrounds and 2) assessing the extent of retinal degeneration in dark-reared Q344ter mice and comparing this to the effect of controlled light-exposure to retinal degeneration.
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Ashlee Rowe of the University of Texas in Austin and her colleagues started off by injecting scorpion venom, formaldehyde and salt water into the hind paws of southern grasshopper mice and common house mice, and compared their behavioural responses.
The SUVs for [18F]FDG-6-P injected mice (Figure 5b) demonstrated a lower background signal in uninfected mice compared to infected mice and compared with [18F]FDG control mice.
The immunogenicity of these formulations was evaluated in mice and compared to CpG containing oligonucleotide.
(C) The α-SMA-positive areas in (A) were quantified in the RBP-J cKO and control mice and compared.
The scaffolds with cocultures were implanted into immune-deficient mice and compared to scaffolds without cells or with HDMEC alone.
To further investigate this, we isolated liver ECs from WT and CD146EC-KO mice and compared their capabilities of migration and tube formation in vitro.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com