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To determine the role of TRPA1 in the generation of mechanically-sensitive currents, we used dorsal root ganglion (DRG) neuron cultures from adult mice and applied rapid focal mechanical stimulation (indentation) to the soma membrane.
For this reason, we extended the population of mice and applied the same vaccination schedules to 8 randomly chosen mice at the same time.
Second, for evaluation of in vivo antitumor effects, we inoculated EMT6 tumors in the right flank (primary site) of mice and applied treatments at day 0 and day 6.
To compare tumor cells grown in vitro to explanted xenograft GFP-expressing MDA-MB-231 breast tumor cells, tumors were resected from female SCID mice and applied onto aligned nanofiber to evaluate the migration potential of biopsied cells on this novel platform, ex vivo.
In this study, we isolated quiescent and activated SCs (QSCs and ASCs, respectively) from both young and old mice and applied gene expression microarray analysis to elucidate the transcriptional profile of QSCs and how it changes when SCs activate during muscle regeneration after an acute injury.
To test this, we used an alternative, very well-established model of experimental liver fibrosis relying on repetitive injections of the substance CCl4 into mice and applied this model for 2 and 6 weeks to WT, Casp-8LPC-KO, Casp-8LPC-KO/RIP3−/−, and RIP3−/− mice.
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Using BL/6N mice and applying a different stress procedure Strekalova et al. [25] reported a decrease in sucrose preference coupled with other behavioural alterations.
In this study, we investigated which administration routes and dosages of EGCG are the most effective for limiting the onset of dystrophic lesions in the same strain of mdx mice and applying the same methods of assessment.
To address this shortcoming, we have examined the cell-surface proteome of the four stem cell lines that are derived from early mouse embryos and applied newly identified protein markers to study differentiation and reprogramming.
It seems Apple is trying to remedy my broken heart by creating a new version of the mouse and applying some sort of multi-touch to the mouse, perhaps with a touch-sensitive housing like the Philips Tapster.
But after just 2 weeks of training, migrant workers with no previous computer experience performed just as well as college students at using a computer mouse and applying that skill to other fine-motor hand skills, the team reports today in Current Biology.
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