Circulating estradiol levels were below the level of detection (10 pg/ml) in all OVX + Placebo mice, while OVX + E2 mice had an average of 246±68 pg/mL.
Again, wt and PD-1-/ mice showed healthy myelin (score 1) while PLPtg mice had an average score of 3±0.81 and PLPtg/PD-1-/ mice showed a higher score (3.83±0.75).
P190B transgenic mice developed an average of two tumors per mouse whereas single tumors were detected in the majority of the control mice (p190B vs. tetO/Neu, P = 0.004, p190B vs. rtTA/Neu, P = 0.016).
BDU/IAEC/2014/NE/39). Female Albino mice with an average weight of 22 25 g (16 mice) were experimented (temperature of 24 ± 3 °C, humidity 40 60% with 12 h light and dark cycles) with a free access to food and water ad libitum.
Il10−/− mice developed an average of 0.8 colorectal tumors/mouse while Il10−/−; Myd88−/− mice were devoid of neoplastic lesions (Figure 7B).
The wild type Cdk2ap1+/+ mice showed an average SL/FW ratio of 1.72, while Cdk2ap1−/− mice showed an average SL/FW ratio of 0.80, which is only 47.0% of the wild type.
In HSV-2 MS-luciferase-infected naïve mice, luciferase activity in the eyes and faces of mice was an average 15-, 580-, and 150-times background on Days 2, 4, and 6 post-challenge, respectively (Fig. 6D).
Wild-type mice had an average score of 4, whereas Hipk2 −/− mice had an average score of 1.
The average number of crossings was reduced from 118.1 ± 2.1 in young WT mice to an average of 97.2 ± 1.6 in adult WT mice (P < 0.0001) and was further reduced to 59.0 ± 1.1 (P < 0.0001) in old WT mice.
The engineered mice lived an average of 38 weeks, compared to 12 weeks for dystrophic mice.
