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However, experimental studies in mice also suggest that chemotherapy has pro-metastatic effects.
Analysis of tight junction proteins in these mice also suggest that treatment with UroA/UAS03 enhanced the expression of Cldn4 (Fig. 6h).
Behavioral studies correlating 2D∶4D in humans and mice also suggest similar, but opposite effects: humans with lower 2D∶4D show greater propensity for aggression [20] [22], whereas inbred mouse strains with larger 2D∶4D were more likely to bite while being handled [23].
Studies of nucleosome occupancy in yeast and mice also suggest that open chromatin influences the formation of DSBs.
The specific decreases in selected glycerolipids observed in CR mice also suggest higher uptake of intracellular lipid stores by autophagosomes.
Recent data from T187A knock-in and Skp2-/ mice also suggest that p27 proteolysis in early G1 is independent of T187 phosphorylation [ 19, 40].
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Comparison of concordant expression changes between PXR+/+ and PXR−/− mice also suggested a PXR-independent association between CMP013 and perturbations to cellular stress, lipid metabolism, and biliary transport.
Experiments using CCR2-deficient mice also suggested that monocytes contribute to T-cell-mediated defense against Mtb.
Recent work by Segal and colleagues in C57BL/6 mice also suggested that neutrophils may be more important effector cells in the brain compared to the spinal cord.
Genetic modulation of MDM2 levels in mice also suggests that p53 regulation during homeostasis may differ from its regulation in cancer tissues (O'Leary et al, 2004).
Recovery of several hundred adoptively transferred IMs from the mLNs of infected mice also suggests that sufficient numbers of IM were present to prime T cells.
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