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Studies in C1q knockout mice also implicate C1q with autoimmunity.
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The NEO analysis in female mice also implicates 9 novel genes.
In cultured human mammary epithelial cells, Abcg2 is thought to be responsible for the SP [ 24]; studies with triple knockout mice have also implicated Abc1a/1b (Mdr1a/1b) [ 36].
Importantly, surgically induced OA disease models in mutant mice have also implicated ADAMTS5 [ 152, 153], DDR-2 [ 103], and Runx2 [ 154] as contributors to the onset and/or severity of OA joint disease.
Therefore, it is essential to further elucidate whether kidney-specific knockout of BHD in the mouse is also implicated in kidney tumorigenesis, and what mechanism is involved.
The absolute requirement for NK cells is however coming under scrutiny as in vivo work in mouse models also implicates monocytes/macrophages as important effector cells (Biburger et al, 2011).
Other studies in mice genetically without B cells also implicate B cells in a number of immunoregulatory interactions that go beyond their clear role as the precursor of antibody forming cells [ 6].
They also implicate activation patterns of discrete brain nuclei as differentiators between reinstating and non-reinstating mice.
This variable penetrance probably reflects differences in the genetic backgrounds of the mice analyzed and also implicates BMP4 as the essential activator of lens induction.
The campaign finance charges also implicate Trump.
He could also implicate senior figures in the Gaddafi regime.
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