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Nuclear factor- κB inhibition in tumour-bearing mice also enhanced antitumour effects of transferred murine naive T cells.
High-voltage electric potential (HELP) stimulation of adult mice also enhanced BDNF levels, increased resistance to cerebral infarction, and improved escape latency in the MWM [ 47].
To explore whether the more robust CD8+ T-cell response measured in Ncf1−/− mice also enhanced virus elimination, virus titers in spleen, liver, kidney and lung tissues were measured after infection with 2 × 10 PFU LCMV WE.
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Recently, we showed that endothelial specific expression of ABCA1 in mice also enhances cholesterol efflux from EC, increases the plasma level of HDL cholesterol (HDL-C), and protects against atherosclerosis [ 10].
Lung dissemination in HCT116 tumour-bearing mice was also enhanced in SC+ORT mice as compared with ORT mice (Fig. 1KN; Table 1).
Intranasal treatment with 100 ng PT followed by inoculation with PR8 7 days later significantly increased viral titers when compared to PBS control-treated mice, and also enhanced virus-associated lung pathology and increased mortality (PT treatment alone has no pathological effects on mouse lungs – our unpublished data).
Furthermore, cardiac expressions of angiogenesis-related vascular endothelial growth factor and endothelial nitric oxide synthase in R6/2 HD mice were also enhanced under oral B307 treatment.
Like human IgM, mouse IgM also enhanced the phagocytosis of small beads, but not large particles by mouse macrophages (Figs. 1, 4).
In addition, life span was reduced in SIRT7-deficient mice, which had also enhanced inflammatory cardiomyopathy compared to wild-type mice.
In WT male mice, PIO treatment also enhanced short-term memory as assessed by MWM, an effect that goes along with modifications of complex I and LDH activity that are similar to the ones observed in PS1-KI females, thereby suggesting a possible common mechanism of action.
The proliferation of neural precursors derived from embryonic mouse cortex was also enhanced by AT treatment in a dose-dependent manner (Figs S2B and 3G– L).
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