Twelve-month-old complex ganglioside knockout mice also displayed significant incidence of tremor and catalepsy.
CNP::EGFP control mice also displayed a significant decrease in corpus callosum (CC) thickness and MBP immunoreactivity.
In vivo, knockout mice also displayed increased tissue damage accompanied by increased inflammatory cytokine expression, decreased anti-oxidant capacity and increased expression of apoptotic markers [100, 101].
In addition, Lrp5-deficient mice also displayed persistent eye vascularization.
DGKβ KO mice also displayed more frequent scratching behavior than WT mice.
In addition to the muscle phenotype, CAG200 mice also displayed reduced fertility.
In addition, conditional Cdk5 KO mice also displayed an increase in behavioral startle reactivity.
DKO mice also displayed unambiguous behavioral arrests that were never observed in WT mice.
Consistent with this, epithelial tissues of WW45−/− mice also displayed hyperproliferation and defects in apoptosis [30].
Hearts from dt mice also displayed no signs of fibrosis or calcification.
These mice also displayed hemorrhages of the brain parenchyma (Figures 5E, F).
