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In MPTP-treated mice, administration of nilotinib significantly reduces the time (Fig. 6).
In MPTP injected mice, administration of nilotinib significantly reduces the increase in PARIS levels.
Despite the absence of detectable CLDIs in mice, administration of this analog still led to significant skin pigmentation.
In mice, administration of azacitidine (AzaC) on days 4, 6, 8, and 10 post DLI increases regulatory T cell (Treg) numbers and prevents GVHD without hindering Graft vs. Leukemia (GVL).
In the in vivo studies on mice, administration of AT1R antagonist (ZD7155) or AT2R agonist (C21) leads to the increase of WAT browning, body temperature and serum adiponectin, as well as the decrease of WAT mass and the serum levels of TNFα, triglycerides and free fatty acids.
In CCI mice, administration of the serine racemase inhibitor, L-serine O-sulfate potassium salt or D-amino acid oxidase on postoperative days 0 to 3 suppressed CCI-induced mechanical allodynia (MA) and pGluN1 expression on day 3 after CCI surgery.
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In addition, it has been reported that, in the mouse, administration of the D1-type receptor agonist SKF 83822 generates seizures [8], [9].
In mouse, administration of CFI to CFI−/− knockout mice cause enhanced cleavage of C3b and appearance of C3 along the basal membrane of the glomerulus [ 16].
In an animal model (mouse), administration of visfatin during superovulation improves developmental competency of oocytes and fertility potential, despite the age.
Brain and whole blood radioactivity concentrations were measured ex vivo by scintillation counting or in vivo by PET in four groups of mice following administration of [18F]flumazenil: awake mice and mice anesthetized with isoflurane, dexmedetomidine, or ketamine/dexmedetomidine.
ST2-deficient mice developed exacerbated EAU compared with WT mice, and administration of IL-33 to WT mice significantly reduced EAU severity.
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