Sentence examples for mice activation of from inspiring English sources

In both glomeruli and cultured mesangial cells isolated from integrin α1-null mice, activation of the p38 and ERK branches of the mitogen-activated protein kinase pathway was also observed.

MW-CNTs are also known for increased micronuclei frequency and chromosomal aberrations, promotion of allergic response in mice, activation of cyclooxygenase enzymes through suppression of systemic immune function in spleen and altered gene expression in the liver [173, 174, 175, 176, 177].

By crossing R26-SmoM2 mice and the TM-inducible form of Cre-driver mice, activation of Hh signaling was achieved.

In female WAP-T mice activation of the transgene, the simian virus 40 (SV40) early gene region flanked by an ∼1.4 kb upstream region of the gene coding for the mouse whey acidic protein (WAP) [20], is initiated during late pregnancy in mammary epithelial (ME) cells concordant with the endogenous Wap gene [21].

In mice, activation of A1 but not of A2A and A3 reduced alveolar fluid clearance [ 22] and may have led to alveolar fluid accumulation.

In both young and older mice, activation of the Akt1 transgene led to statistically significant reductions in the levels of all of these genes.

As previously mentioned, in human and mouse, activation of GPR120 under the stimulus of the PUFAs could stimulate the ERK1/2 phosphorylation signal transduction cascade [ 5, 8, 10, 17].

In mouse embryonic fibroblasts (MEFs) derived from TRAF2- or TRAF6-deficient mice, the activation of ASK1 induced by hydrogen peroxide was dramatically attenuated and both JNK and p38 activities were also reduced [ 11].

Macrophages isolated from these mice impair activation of IRF3 post DNA viral infection.

Here, we investigated the role of Mig-6 in regulating adenocarcinoma progression in the lungs of genetically engineered mice with activation of Kras.

In mice, selective activation of CAR significantly alleviated high fat diet-induced obesity and type 2 diabetics via a combined inhibition of lipogenesis, fatty acid synthesis, and gluconeogenesis, as well as the increase of energy expenditure in brown adipose tissues (Dong et al., 2009; Gao et al., 2009; Masuyama and Hiramatsu, 2012).