Sentence examples for mice accumulation of from inspiring English sources

In aged mice, accumulation of RanGAP1 together with polyglutamine is shifted to perinuclear and cytoplasmic areas.

Furthermore, while the absolute numbers of both SP and B220+ DN T cells progressively increased in the periphery of gld mice, accumulation of B220+ DN T cells occurred at a rate that significantly exceeded that of SP T cells eventually resulting in predomination of the repertoire by B220+ DN T cells.

Notably, in these mice, accumulation of p62 accelerates liver damage, which leads to the development of hepatic cancer via persistent activation of the Nrf2 pathway [ 117– 117].

Also, in 3xTg-AD and arcAβ mice, accumulation of intraneuronal Aβ correlates with early cognitive deficits, preceding the appearance of APs [ 11, 65].

In prion-diseased mice, accumulation of misfolded prion protein (PrP) causes persistently high levels of PERK-P and eIF2α-P, and hence sustained translational failure.

In K14MycER mice accumulation of differentiated sebocytes within the SG was greater at low and intermediate 4OHT doses than at high doses.

In the BM and spleen of Sca1-MafB mice, accumulations of B220lowCD138hiFSChiSSChi plasma cells could be clearly seen by 12 months of age (Supplementary Figure 7B and C).

Total BALF macrophage numbers were determined in BALB/c mice and NOD SCID mice, where accumulation of macrophages in response to CS exposure was maintained in the absence of functional T- and B-cells.

However, compared to those of 2-week-old WT mice, the SMGs of 2-week-old homozygote MYCN Tg mice show accumulation of immature neuroblasts microscopically.

In the hMR-Tg mice, the accumulation of vaccine in DCs was significantly greater than in WT mice, and was exclusively observed in hMR+DEC-205−CD103− DCs.

Based on these studies, we also analysed the Slc9a6 mutant mice for accumulation of phosphorylated tau, and found small increases in the soluble brain fractions of mutant mice (Supplementary Fig. 2).