Sentence examples for mice accumulated high from inspiring English sources

These mice accumulated high levels of putrescine and exhibited a depletion of spermine and spermidine.

However, mice accumulated higher Cr levels than rats at ≥ 170 mg/L SDD, resulting in a ~ 2-fold increase in the number of differentially expressed genes.

Although CerS2 null mice accumulate high levels of C16-ceramide, no liver damage was observed following LPS/GLN treatment.

In line with this hypothesis is our finding that Slc10a1 −/− mice accumulate high amounts of BAs in the circulation if they are challenged with 0.1% UDCA, and this hypercholanemia is inducible in Slc10a1 −/− mice with normal or minimally elevated serum BA concentrations.

Moreover, AM+/− mice accumulate higher oxidative stress and insulin resistance in aging compared with wild-type (WT) mice [ 11].

Our data also reveal that Bim-/ mice accumulate higher frequencies of Treg cells showing the importance of cytokine withdrawal death in regulating peripheral Treg cells.

To add new insights into the pathogenesis of muscular dystrophy and to determine the basis for the milder phenotype observed in adult mdx mice, compared with young mice and to human patients, we crossed the mdx mice with IL-6 overexpressing mice, which accumulate high levels of circulating IL-6 since early phases of life (34).

Pr1 plants accumulated high levels of cyanidin (data not shown).

To test the causative role of mtDNA mutations in aging we have developed the mtDNA mutator mouse that accumulates high levels of point mutations due to a proofreading deficiency of the mitochondrial DNA polymerase (POLG) [ 12].

On a molecular level, mutator mice accumulate extremely high levels of mtDNA point mutations and low levels of multiple mtDNA deletions (28, 55, 56).

These mice accumulated creatine to very high levels (four-fold above wild-type), which was associated with left ventricular (LV) hypertrophy and dysfunction.