In comparison to matched 24 h LD housed mice, a significant reduction in adiposity was observed in 22.5 h LD conditions (Fig. 2a).
In tumor-bearing mice, a significant correlation was observed between the accumulation in the tumor as well as tumor-to-blood ratio of 111In-DTPA-CTT and gelatinase activity.
In testing the therapeutic potency of compound 10 on CT26-xenografted BALB/c mice, a significant reduction in tumor size comparable to that of cisplatin was found when administrated via the i.p. route.
When comparing C57Bl/6 MCAT +/+ mice and C57BL/6J WT mice, a significant decrease in LS was identified in the WT mice at 24 h (MCAT = −23 ± 5% vs. WT = −15 ± 4% p < 0.01) and 48 h (MCAT = −23 ± 7% vs. WT = −15 ± 4.3% p = 0.04) post-CLP which correlated with significant increase in the level of cardiac oxidative stress following CLP.
Interestingly, in hippocampus of 2 months old mice, a significant peak in variant proteins was observed.
In a recent paper describing HIV-1 infection of primary mouse T cells from hCD4/CXCR4 transgenic mice, a significant pre-integration block was reported [43].
In C57BL/6 mice, a significant current decrease was observed although it was less prominent (by about 25%) than reported in rabbit and pig detachment models [27], [32].
In both CY-treated WT BALB/c and R4A Tg BALB/c mice, a significant elevation in BAFF was observed (Figure 4 and data not shown).
In AKAP5 mutant mice, a significant fraction of PKA becomes localized to dendritic shafts and this correlates with increased binding to microtubule associated protein-2 (MAP2).
In treated mice a significant decrease in AHR as well as in eosinophil counts in BALF and levels of IL-4 and eotaxin in the lung were observed (Figure 1).
For example, regardless of the two cell types, we observed in mice a significant innervation of the external part of the globus pallidus and particularly of the lateral pallidal parvalbumin-containing neurons.
