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Upon adoptive transfer of these CD8+ T-cells into Chlamydia infected mice, a reduction in bacterial load can be measured in the spleen.
In C/EBP- β knockout mice a reduction in leptin but also a decrease in fat mass was observed [ 78].
In fact, in mice a reduction of CD40 expression seems to be responsible for the reduced DTH response in an IL-12-dependent way [ 49].
By ablating Flk1 in the Isl1-cre mice, a reduction in the number of Isl1-ECs was observed in the endocardium, suggesting that Flk1 is required for the formation of the endocardium.
In such mice, a reduction of SIRT7 levels was accompanied by increased p53 activity, subsequently resulting in enhanced cardiomyocyte apoptosis (Vakhrusheva et al. 2008; Voelter-Mahlknecht et al. 2006a).
Compared with control mice, an anorexic effect of LPS was observed earlier in ob/ob mice: a reduction in food intake was noted at 8 hours and lasted until 3 days after injection (Fig. 4A).
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Analysis of mature vestibular hair bundles reveals an absence of tip links in the av3J/av3J and v2J/v2J mice and a reduction in av6J/av6J mice.
Besides, studies in which the PAI-1 gene was disrupted in ob/ob mice show a reduction of adiposity in these mice.
In contrast, untreated transgenic mice exhibited a reduction in lipid metabolites vs. wild-type mice.
Analysis of Haematoxylin and Eosin (H&E) stained sections of mammary tumours from 13-week-old mice revealed a reduction in tumour progression in PyVmT/Usp18 KO mice.
Nerve-crush injury on P5 Mag-null mice induced a reduction in MNs count respect to Wt mice (72±2.3% versus 80±3.4% MN count, respectively, Figure 2b).
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