Your English writing platform
Discover LudwigExact(5)
Similar to the EM observations from Nrf2−/− mice, a previous report showed that autophagosome-like structures accumulated in the RPE of human AMD eyes [50].
While we did not investigate M2 alone in mice, a previous study has shown that vaccination with M2 alone is capable of protecting mice against heterologous strains of influenza virus challenge, including H5N1 [9].
Although we did not directly measure Tβ4 levels in treated mice, a previous study showed significantly increased levels in the hearts and skeletal muscle of mice after treatment with 400 micrograms of Tβ4 via intraperitoneal injection.[40] Chronic exposure of Tβ4 could potentially lead to the development of anti-Tβ4 antibodies.
Although nNOS inhibitor I in our hands did not affect LTP in wild-type mice, a previous study reported that nNOS inhibitors produce a major loss of particularly the later phases of LTP (Hopper & Garthwaite, 2006).
Overall, our phenotypic data in humans and mice are in accord with previous studies in WAS: the number of total B cells and MZ B cells are decreased in both human WAS patients and WASp−/− mice; and similar to our observations in mice, a previous study also suggests that the relative percentage of immature peripheral B cells is increased in WAS patients.
Similar(55)
Finally, this study revealed that neither TLR1−/− nor TLR6−/− mice were any more susceptible to LVS infection than control mice, although a previous study reported an exclusive role for TLR6 in the pro-inflammatory cytokine response of BM-derived dendritic cells to LVS in vitro [39].
Interestingly, while our current data and previous studies using APP transgenic mice generating normal human Aβ [ 10, 24] suggested that apoE4 redistributed Aβ deposition to CAA as compared to mouse apoE, a previous study using mice expressing human Dutch/Iowa (E22Q/D23N) mutant Aβ showed an opposite pattern [ 38].
To examine the possibility that outbred CD-1 mice model human founder populations, we compared the average MAF differences observed among subpopulations of CD-1 mice to a previous study of human populations (Figure 6).
In a separate study also published today in Immunity, immunologist Ruslan Medzhitov of the Yale University School of Medicine and colleagues confirm that mice with a previous type 2 response to bee venom have a greater resistance to potentially lethal doses of the stuff later on and that IgE-lacking mice miss out on this protective effect.
The dosage was reported to be equivalent to the maximal dosage for humans and was well tolerated by mice in a previous study [24].
Two of the mutant mice with a previous history of convulsion exhibited it again on handling, while one without a history of behavioral convulsion, also exhibited generalized tonic seizure.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com