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Then they fed half of the mice a normal diet and half a high-fat diet.
For example, in a UCLA study, researchers gave more than 100 genetic variations of mice a normal diet for eight weeks, followed by a high-fat, high-sugar diet (aka, the SAD "Standard American Diet") for another eight weeks.
Thus, we fed BALB/c mice a normal diet with OPP for six weeks and looked for signs of toxicity to confirm that OPP is safe.
In bone marrow from mdr1a1b /– knockout mice, a normal percentage of SP cells was obtained, suggesting that MDR1 is not correlated with the SP cells identified by Hoechst (Uchida et al, 2002).
We fed the mice a normal [0.9% (w/w) NaCl] or high-sodium [4% (w/w) NaCl] diet for 7 days before the extraction of the kidney proteins and collection of blood samples.
To validate the hypothesis that Ca and exogenous PTH 1 34 have synergistic effects on bone formation in adult mice, and to identify the related mechanisms, we fed 6-week-old male mice a normal or high-Ca diet, and subcutaneously injected them with vehicle (saline solution) or exogenous PTH 1 34 (80 μg/kg per d) for 4 weeks.
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For some experiments, male C57BL/6 mice on a normal mouse chow (Ssniff, Soest, Germany) were used.
When introduced to another mouse, a normal mouse will typically investigate the new mouse by walking over and sniffing it.
Compared to FXR+/+ mice, FXR−/− mice display a normal architecture and β-cell mass but the expression of certain islet-specific genes is altered.
As shown in Figs. S4A and B, neither islet size nor β cell mass were different between PI4KIIα TG mice and WT mice fed a normal chow diet.
Sinclair says the hypothesis is that when given resveratrol, the health of mice on a normal diet will resemble that of mice on a calorie-restriction diet just as the health of the mice on the high-fat diet resembles that of mice on a normal diet.
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