More detailed analysis with homogeneous groups of mice with transplanted SL2 lymphoma in DBA/2 mice showed a dose response effect in the dose range of 5,000 200,000 IU IL-2 given on five consecutive days [ 12].
To determine the relative susceptibility of the mice, a dose-response curve was obtained to observe the fraction of mice infected as a function of the viral dose delivered.
There is no knowledge about diazepam and MPEP effects in 129P3 mice specifically so a dose response curve was included in the open field test.
On Day 0 female BALB/c mice (n=7 8/group) were injected intraperitoneally with a dose response of CAM-3003 (10 mg/kg, 1 mg/kg and 0.1 mg/kg), CAT004 (isotype control 10 mg/kg) or vehicle alone.
There was a dose response towards normal in mice that consumed 1 or 2% dietary AAFA™ for: apoptotic figures in the duodenal crypts, liver weight, WBC and RBC counts.
After the maintenance phase of self-administration training, separate groups of mice were taken through a dose-response.
Strikingly, Dclk3, which encodes a protein kinase, displayed significantly altered hepatic abundance in only female mice along the dose response study, but was primarily altered in only male mice along the time-course study, with modest changes observed at 6 h post-exposure in females [ 42].
The mouse brain DA time course and dose response experiments utilized an Agilent mouse 22K feature oligonucleotide microarray, while the mouse blood dose response and brain PbTx TC utilized the 44K mouse whole genome array.
Acute skin reaction in the whole irradiation field around the tumor was evaluated in the period from 8to5858 days after the irradiation in all mice used for dose response evaluation.
Peptide sequences with binding scores below 0 did not elicit a proliferative response in these transgenic mice; however, a dose-dependent response was seen for peptides with binding scores greater than 0 (Fig. 2).
