In mice, an administration of peptide fragment derived from Clostridium perfringens enterotoxin decreased the protein expression of claudin-4, a TJ protein expressed in type I AEC type I AEC and type I AEC type II AEC junctions, with increased pulmonary edema in response to ventilator-induced lung injury [ 22].
In BALB/c mice, a single administration of either IgG or F ab' 2 could prevent the establishment of infection with a sublethal dose of PR8 virus when given as early as 7 days prior to exposure to virus.
Interestingly, in C56BL/6J AAV-HBV mice, a single administration resulted in a dramatic reduction in both HBV DNA and HBsAg (>1 log decrease for the DNA), and a significant decrease was sustained until day 105.
In the mouse model, intrauterine SP-A administration results in prompt labor.[31] More research is required to establish the relative maternal and fetal contribution to inflammation at term.
Mice (N = 114∶58 wild type and 56 transgenics) were first treated with increasing doses of formulated MLN-273 (0.10.2, 0.3, 0.4, 0.4, and 0.5 mg per Kg of mouse weight), following an administration cycle of two injections per week for two weeks and one week of rest (Figure 3A).
SPECT imaging of a mouse after administration of a 99mTc-radiolabeled virus showed clear localization of radioactivity to the liver.
Present investigations were planned to study the effect of Lantana camara leaf powder, Lantana camara methanolic extract (LCME) and lantadene A administration on mice intestinal motility using neostigmine as a promotility agent.
Our previous study has indicated that AF increases glucose tolerance and insulin secretion in NMRI mice after administration through a gastric gavage in a single dose at 150 mg per mouse.
No apparent hepatotoxicity was observed in neonatal mice following Ad vector administration.
Next, in order to examine anti-Ad antibody production in neonatal mice following Ad vector administration, the anti-Ad antibody titers were evaluated by ELISA.
In CD1 mice, the administration of a 10 nmol opioid dose elicits a profound decrease in response to successive doses of morphine [46].
