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Prior to surgery, she received 0.5 mg of atropine and 2 mg of midazolam intramuscularly.
After the administration of 2 g of pralidoxime (PAM) and 0.5 mg of atropine, the mother felt better.
However, case 3 (and many other cases in the cohort (5)) received over 200 mg of atropine soon after admission without effect on their BP.
If severe cholinergic symptoms were observed during or after irinotecan infusion, 0.25 mg of atropine given as a subcutaneous injection was recommended and prophylactically administered during subsequent courses.
He received atropine until atropinisation: 40 mg of atropine over 30 min. Ten minutes later, he became pulseless and ECG showed ventricular tachycardia, and then ventricular fibrillation.
A decrease in systolic BP below 90 mmHg was treated with 5 mg of intravenous (IV) ephedrine and HR < 45 BPM with 0.5 mg of atropine.
Similar(47)
Patient was successfully resuscitated with in 3 min after being intubated and receiving 1 mg of intravenous atropine and 1 mg of intravenous epinephrine.
Briefly, mice were anesthetized with an intraperitoneal injection of a combination of ketamine, medetomidine, and atropine (KMA): 7.5 μl/g body weight of induction KMA mix (consisting of 1.26 ml of ketamine, 100 mg/ml; 0.2 ml of medetomidine, 1 mg/ml; 1 ml of atropine, 0.5 mg/ml; and 5 ml of NaCl, 0.9%).
To maintain anesthesia, a 5.0 μl/g body weight bolus of KMA mix (consisting of 0.72 ml of ketamine, 100 mg/ml; 0.08 ml of medetomidine, 1 mg/ml; 0.3 ml of atropine, 0.5 mg/ml; and 18.9 ml of NaCl, 0.9%) was administered through an intraperitoneal catheter every 30 minutes.
Rats were pretreated with 0.1 ml of atropine sulfate, anesthetized with a mixture of ketamine HCL (80 mg/kg, i.p).
As per institutional practises, the patients were treated with 10 15 mg bolus dose of atropine followed by 10 15 mg IV atropine infusion in 0.9% normal saline over about 12 hours.
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