The phrase "meticulously refined" is correct and can be used in written English.
It means something has been carefully and thoroughly improved or perfected. Example: The chef's signature dish was meticulously refined over years of experimentation and was now considered a masterpiece by all who tasted it.
Take that, meticulously refined Deutsch Fussball-Bundevelopmentnt structure!
They wrote meticulously refined, elegant, and sophisticated epyllia (brief epics), lyrics, epigrams, and elegies.
Stylistically, The Duke of Burgundy is an aesthete's dream – meticulously refined, delicate as a fritillary's wing.
What to the untrained eye might look like a bunny with a permanently startled expression is, in fact, a meticulously refined modernist work.
Mr. Williams was himself a poet, essayist, photographer and graphic artist — talents he brought to the meticulously refined design of the approximately 100 books of avant-garde poetry and fiction, folk art and photography that Jargon has published since 1952.
West meticulously refined the production, adding string arrangements, gospel choirs, improved drum programming and new verses.
The completion method reduces the time-consuming work of meticulously refining the network of reactions, the set of biomass metabolites and the selection of appropriate metabolites as nutrients and secretions (e.g. byproducts, toxins and signaling molecules), which are needed to produce a feasible FBA model.
Since we're told which of two 19th-century still lifes is an original and which is a fraud, it's hard not to notice the contrast between the refined, meticulously rendered "Grapes in a Porcelain Bowl" and the garishly artificial "Spirit of '76: Red, White & Blue," even though both appear to be signed by the American painter George Henry Hall.
Amazon is a meticulously optimized product refined by decades of intense usage.
But if Mr. Hurt gives a meticulously detailed performance, he is still so innately refined that Brett never quite registers as an authentic blue-collar type, either vocally or in his body language.
Jewelry, which is always meticulously rendered in these paintings, was designed to convey not only wealth but also refined taste and imperial superiority.
