Sentence examples similar to methylphenidate delivery from inspiring English sources
To evaluate the pharmacodynamic effects of an experimental (EXP) delivery of methylphenidate (MPH) in children with attention-deficit/hyperactivity disorder and to investigate the situational nature of effects in laboratory classroom and playground settings.
OROS-MPH uses a mechanical mode of delivery, releasing methylphenidate in a biphasic manner as it transits through the gastrointestinal tract [ 9].
ADHD-RS-IV = Attention-Deficit/Hyperactivity Disorder Rating Scale IV; dMPH = dexmethylphenidate; ER = extended-release; IR = immediate-release; MPH = methylphenidate; CD = controlled delivery; OROS = osmotic-release oral system; SR = sustained-release.
In contrast to lisdexamfetamine, alterations in gastrointestinal transit time and first pass metabolism in the liver may have an impact on the delivery of methylphenidate from OROS-MPH to sites of action [ 9].
In addition methylphenidate transdermal system provides consistent delivery of medication over the course of the day, acting for approximately 12 hours.
This study was designed to develop a drug-in-adhesive (DIA) type transdermal drug delivery system (TDDS) for D-threo-methylphenidate (D-threo-MP) that could be further developed for treating Attention-Deficit/Hyperactivity Disorder (ADHD) in children.
Transdermal drug delivery is an effective and safe means of administering methylphenidate for patients with ADHD.
Depending on the delivery profile of the various compounds, the exposure to stimulants such as methylphenidate may vary over the day, potentially resulting in declining efficacy towards the evening hours [ 19].
To determine the safety and efficacy of switching from an oral methylphenidate formulation to the MTS, the effects of an abrupt switch from oral methylphenidate ER (Ritalin LA, Concerta, or Metadate controlled delivery [CD]) were assessed in a 4-week, open-label study [ 31].
Methylphenidate -- Brand name: Ritalin.
Sensitization of mice to methylphenidate.
