Sentence examples for methylation values in from inspiring English sources

The three states and the thresholds we use are supported by the distribution of methylation values in our data, but including direct modeling of counts of methylated versus unmethylated instances of a CpG site (Ziller et al., 2013) into our approach is a promising future direction.

The distribution of methylation values in each group of samples is shown in Figure 1b.

Their methylation values in Figure 1 show cases in which methylation is higher in females than males or vice verse.

Of these genes, fourteen showed higher methylation values in primaries compared to metastases in our cohort.

Batch effects affect CpG methylation values in an irregular way and specialized correction techniques are needed.

Methylation values in blood were available for 280 patients (185 normal colonoscopies and 95 adenomas).

The median methylation value in the respective patient group was used as the cut point for dichotomization.

Importantly, the methylation value in the tumor tissue was higher (0.557) than that of the adjacent liver tissue (0.008).

For the SNPs that were selected in common between genotype and DNA methylation, we used the one-sided t-test that rejects the null hypothesis that the microarray measurement of genotype is as large as the DNA methylation value in favor of the microarray measurement of genotype is more than the DNA methylation value.

Such conservative approach has the advantage to take simultaneously into account the read coverage and the CpG content of the considered CGI, and the difference in the methylation values measured in the two replicas.

Despite the same patient origin for FF and FFPE tumor samples, tumor cell heterogeneity might not be the same in different tissue sections from a given tumor piece, thereby giving rise to a degree of variation in the methylation values observed in FF samples compared with those of matched FFPE samples.