Sentence examples for methylation patterns and from inspiring English sources

Therefore, 21 CpG nucleotides up to 523 bp upstream of the ATG start codon were analyzed for global methylation patterns and total number of methylated cytosines (Fig. 1).

Dietary methyl deficiency (folate, choline, and methionine) in animal models alters hepatic DNA methylation patterns and induces liver cancer in the absence of a carcinogen [ 286].

Bird, A. DNA methylation patterns and epigenetic memory.

This study was designed to assess the relationship between alterations in sperm DNA methylation patterns and semen parameters in subfertile males.

The goal of this review is to discuss maladaptive changes in β-cell DNA methylation patterns and chromatin architecture, and their contribution to diabetes pathophysiology.

To investigate the effect of vitrification on Dnmt1o, Hat1, and Hdac1 promoter CpG island methylation patterns and messenger RNA (mRNA) expression levels in mouse metaphase II (MII) oocytes.

Given the apparent heterogeneity of DNA methylation patterns and the multitude of biological processes involved it was suggested that DNA methylation evolved in every phylogenetic clade towards a specific role in controlling gene expression.

Ultra-high-throughput sequencing is emerging as an attractive alternative to microarrays for genotyping, analysis of methylation patterns, and identification of transcription factor binding sites [29].

Our results in this investigation suggest that cDNMT1, cDNMT3A, and cDNMT3B are highly active in early embryos for the maintenance of methylation patterns and de novo methylation.

Using a similar approach, Everhard et al. have previously shown a correlation between promoter-wide methylation patterns and MGMT mRNA expression [12].

Our data provide detailed insight into global DNA methylation patterns and their relationship to gene expression in the human chorionic villi.