Sentence examples for methylation in solid from inspiring English sources

We next examined methylation in solid tumours.

5-AZA-CdR reactivates many genes that suppress malignancy and are silenced by aberrant DNA methylation in solid tumors (Table 1).

To ascertain whether this region is associated with aberrant methylation in solid tumors and could potentially be a marker for disease, we profiled tumor and normal paired samples from the Cancer Genome Atlas.

We have reported previously ASS1 methylation in solid tumour cells but this is the first study to reveal methylation as a determinant of sensitivity to arginine depletion in malignancy.

Furthermore, the selective event may occur during or after the process of invasion/metastasis, as we and others have not found evidence of methylation in primary solid tumors [38].

Several evidences, including the detection of ROBO1 methylation in primary solid tumours and the predisposition of mice carrying an inactivated ROBO1 allele to generate lymphomas, support the role of this gene as a classical TSG [32] [34].

RASSF1A is a tumor suppressor gene which is epigenetically inactivated by cytidine methylation in many human solid tumors.

A phase II clinical study using hydralazine in combination with standard cytotoxic chemotherapy is being planned as proof of concept that the reactivation of tumor suppressor genes silenced by DNA methylation increases chemotherapy efficacy in solid tumors.

To determine if the methylation of this interval has prognostic value in solid tumors, we determined the methylation index for a range of tumors and adjacent normal tissues using the Infinium HumanMethylation450 BeadChip array.

Association of mir-124-3 mir-124-3 mir-124-3 reCGIrence-free survival in solid tumethylationur knowledge, handnot been described as yet.

Differential methylation in 10 types of solid tumors collected by TCGA.