Sentence examples for methylation in maintaining from inspiring English sources

These results highlight the importance of DNA methylation in maintaining stem cell homeostasis during the development and regeneration of ectodermal organs.

The role of DNA methylation in maintaining stemness induced pluripotent stem cells from human extraembryonic amnion cells is discussed.

A role of DNA methylation in maintaining the embryonic lineage was shown to depend on methylation of the TE-specific factor Elf5, whose expression is regulated by DNA methylation, and which positively regulates Cdx2 and Eomes expression [2].

The relationship between histone modifications and DNA methylation in maintaining gene silencing has been studied at the chromosomal level [ 28].

These results validate the bioinformatic analysis above and suggest a role for methylation in maintaining suppression at some non-imprinted loci in oocyte.

Despite the importance of lysine methylation in maintaining cellular homeostasis, the development of proteome-wide approaches for detecting this modification has been limited and has proven technically difficult.

- Such experimentally induced reprogramming provides a cellular model to assess the functional contribution of both cancer-specific and lineage-associated methylation changes in maintaining the malignant cellular state.

Proudhon, C. et al. Protection against de novo methylation is instrumental in maintaining parent-of-origin methylation inherited from the gametes.

In contrast to promoter methylation, gene body methylation may be important in maintaining active transcription.

Our findings might not fit into the model that histone methylation and DNA methylation are closely corollated in maintaining the repressive state of genes [ 3].

In addition, CTCF also has barrier function to prevent spreading of heterochromatin structure and DNA methylation which plays a critical role in maintaining methylation-free zones [39], [40].