Sentence examples for methylation in buccal from inspiring English sources

Exact(12)

Methylation in buccal cell samples was more variable, with an average difference of around 2%.

We have observed particulate matter-associated differences in DNA methylation in buccal cells.

A study of DNA methylation in buccal cells showed significant alterations in children with in utero smoke exposure [ 117].

We examined genome-wide patterns of DNA methylation in buccal cell samples collected from 37 MZ twin pairs discordant for asthma at age 10.

Another limitation of our study is that we compared DNA methylation in buccal cells (a mixed-cell population) to CD4+ lymphocytes (a very select population).

Maternal prenatal smoking was associated with lower LINE-1 methylation in buccal cells of preschool children with glutathione S-transferase mu 1 (GSTM1 -null GSTM1 -nullhereas there was higenotypehylation in the GSTM1-present children (Breton et al. 2009).

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Similar(48)

We assessed genome-wide patterns of DNA methylation in twin buccal cell DNA using the Infinium HumanMethylation450 BeadChip from Illumina.

In a very recent 50 K array-based DNA methylation analysis, several identical changes in DNA methylation in the buccal epithelium of six children with FASD have been obtained, primarily in genes related to glutamatergic synapses, protocadherins and hippo signaling [ 50].

Yet, two smaller studies with 10 20 years of follow-up demonstrated that at specific genomic loci, DNA methylation in blood and buccal swab samples can remain remarkably stable (Feinberg et al., 2010; Talens et al., 2010).

While our study concurs with these finding for peripheral blood, we did find non-significant increase in DNA methylation at this region in buccal cells of children conceived through ART, so small differences in DNA methylation cannot be ruled out for this locus.

Recently, Breton and colleagues sampled children living in Southern California in one of the first large cohort studies analyzing DNA methylation of asthma genes in buccal cells [ 17].

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