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Figure  3c shows schematically the contrast between the methylation status among the 27 CpGs of the "C" clones and the "W" clones.

Second, we identified a subclass of CGIs that have an unusually high contrast between the methylation state of the CGI and the flanking shores.

Resorts that contain at least one methylated and unmethylated ultrastable CpG (top panel) have a strikingly high contrast between the low methylation level of the CGI compared to the highly methylated shores and shelves.

The striking contrast between the consistent methylation-free status of three separate G + C-rich, CpG-rich integrants and the reproducible dense methylation of four unrelated A + T-rich, CpG-rich sequences of the same length indicates that base composition is a strong determinant of DNA methylation status.

In contrast, methylation rates between birth and postnatal day 4 were stable in term infants (figure 1).

The contrast between the United States and Europe is stark.

The contrast between North and South is stark.

Still, the contrast between them is stark.

The contrast between Mackinac Island and Detroit is simply boggling.

Consider the contrast between Utah and Vermont.

5.Use strong contrast between foreground and background.

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