Sentence examples for methyl cycle which from inspiring English sources

Methionine, as a constituent of proteins, is also critical to biochemical pathways, including the "methyl cycle" which generates the key metabolite S-adnosylmethioinine (AdoMet) [ 32].

Interestingly, the compounds involved in the methyl cycle, which is a sulfur salvage pathway (see Fig. 1), were not recovered in the highest score stories found in our first analysis.

On the other hand, Doherty et al. indicated that LuxS fulfills primarily a metabolic role in the activated methyl cycle, which generates the S-adenosylmethionine required by methyltransferases and recycles the product via methionine as well as cell-to-cell signaling [ 54].

This enzymatic activity is central to an activated methyl cycle in which methyl groups are attached to nucleic acid precursors, proteins and other metabolites.

Metabolic forms of folate are involved in synthesis of nucleotides and in the methionine cycle, which generates methyl groups that are essential for DNA methylation.

Theses enzymes are involved in the S-adenosyl-methionine (SAM) cycle, which participate to methyl or propyl-amine group transfer, and to polyamine synthesis [45].

Homocysteine is formed in the methionine cycle, which is involved in one-carbon methyl group-transfer metabolism, and it acts as a methyl donor when it is converted to S-adenosyl-methionine.

In addition to its importance in protein synthesis, MS is a key enzyme of the methionine cycle, which maintains the cellular level of the methionine derivative, S-adenosylmethionine, the methyl donor in a wide array of cellular processes including DNA, RNA and protein methylation.

However, our assumption is based on the 'hydrocarbon-pool' cycle, which has been considered as the origin of series of MTH reactions and gives C 2 –C 4 olefins and methyl-aromatics as the primary products [4].

Cystathionine γ-synthase and -β-lyase likely provide homocysteine as an acceptor for methyl transfer from S-methylmethionine, catalyzed by homocysteine S-methyltransferase [ 55], while Met synthase is essential to recycle homocysteine produced in the S-adenosylmethionine cycle, which appeared highly active according to the high representation of the Met adenosyltransferase activity category.

Most of the other genes commonly regulated in the microarrays were also found to significantly impact chronological lifespan when deleted, including ADO1 (adenosine kinase), which links the methyl cycle with de novo purine biosynthesis.