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Few methods reported the quantitation of FEX in pharmaceutical dosage forms using spectrophotometric methods [10], LC methods with ultraviolet detection [11 13], and capillary electrophoresis [14, 15].
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A simple, accurate, precise and sensitive high-performance liquid chromatographic (HPLC) method with ultraviolet detection was developed to quantificate lamivudine (3-TC) in human plasma samples from bioequivalence studies.
Ionic liquid 1-butyl-3-methylimidazolium bromide-methanol-based ultrasonic-assisted extraction (ILUAE) was used to extract tilianin and acacetin from the aerial parts of Agastache rugose (A. rugose), and simultaneously determined by reversed phase high performance liquid chromatographic (RP-HPLC) method with ultraviolet detection (RP-HPLC-UV).
To allow such evaluations and to provide a general, sensitive, rapid and simple method for the analysis of compounds containing the 1,5-diaryl-3-oxo-pentadienyl scaffold, we developed an HPLC method with ultraviolet detection for their detection in various biological matrices of a relevant preclinical species, i.e. the rat.
Water concentrations of florfenicol were determined using a HPLC method with ultraviolet (UV) detection.
Paclitaxel concentrations in urine were determined using a validated HPLC method with ultraviolet (UV) detection (Huizing et al, 1995).
TMZ concentrations in plasma and normal brain microdialysate samples were determined using a validated reversed-phase high-performance liquid chromatography method with ultraviolet detection.
The artemisinin content of filled capsules was analyzed by the Unit for Pharmacokinetics and Drug Metabolism, Department of Pharmacology, University of Gothenburg, Sweden, using a HPLC method with ultraviolet detection.
TMZ concentrations in plasma, normal brain, and brain tumor homogenates were determined using a validated reversed-phase high-performance liquid chromatography method with ultraviolet detection.
The simultaneous assay of 5-FU and 5-FUH2 in human plasma was performed by a validated, nonradioactive reverse-phase HPLC method with ultraviolet detection.
Plasma acetaminophen concentration was determined using a validated high-performance liquid chromatography (HPLC) method with ultraviolet detection at PRA International, Assen, the Netherlands (calibration range = 0.500 50 μg/mL).
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