This paper reviews another method, which poses the calculation of the bounds of the probability of failure as a reliability-based-design-optimization problem.
It is based on finite difference methods on fixed Cartesian meshes which pose a challenge that the moving boundaries intersect the grid lines in an arbitrary fashion.
Indeed, such approaches are becoming increasingly more difficult owing to the emergence of new forms of complex RNA, which pose further challenges to these prediction methods (reviewed in [ 118]).
Until recently, computational methods hadn't been applied to making better organic semiconductors, which pose a different set of challenges, says Aspuru-Guzik.
The power flow equations are nonlinear and nonconvex, which pose challenges to the traditional deterministic OPF using the interior-point method.
However, only few studies have extended this method to mitochondrial disorders (Clarke et al., 2013; Leoni et al., 2012; Shaham et al., 2010), which pose significant challenges, owing to their genotypic and phenotypic heterogeneity combined with small patient populations.
Third, our analytical method has not been validated for all categories of foods, although it has been validated for oils and fats, which pose the greatest challenges for the analysis of trace levels of lipophilic compounds.
Such results further tease out the underlying mechanism of how payment methods influence spending behavior, which poses important implications for both consumers and merchants, as well as designing of digitalized payment in the future.
Here, we describe how to produce a Bacillus subtilis SSB probe which posed significantly different challenges than published methods for E. coli SSB.
Due to the variety of testing conditions and methods to express cartilage quality response, only qualitative comparison was possible, which poses limitations to the study.
