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But Dr. Vogelstein said DNA-based markers of cancer could become a better diagnostic than the present methods, which depend on detecting cancer-linked proteins.
The researchers found that the Oncotype test predicted such unfavorable pathology more accurately than existing methods, which depend mainly on the Gleason score based on how the biopsy sample looks under the microscope.
This is quite different from many fast multipole methods which depend on analytical expansions of the far-field behavior of K, for |x−y| large.
Since, in the naive library, each cassette contains all possible combinations of the polypeptide sequences it encodes, much longer regions can be optimized than was possible with methods which depend on a simple selection from the naive library.
Although our findings suggest that the proposed assessment framework for novelty evaluation is unable to provide a 'one-size fits-all method', it does enable us to overcome some of the limitations of current evaluation methods which depend on subjective judgements for rating.
Attempts to model these interactions have generally taken the form of amino acid base recognition codes or purely sequence-based profile methods, which depend on the availability of extensive sequence and structural information for specific structural families, neglect side-chain conformational variability, and lack generality beyond the structural family used to train the model.
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The cold walls introduce a delineation error for threshold-based delineation methods which depends on the size of the walls, the spatial resolution, and the contrast [17].
The structure of the populations used in this study can be described through the distribution of distance values (see Methods), which depends on the value of the mutation rate, the selective pressure dominant, and the time of evolution.
To address this problem, we explicitly defined a monotonic transformation independent of ranking methods, which depends on training set of likely true variants (2) train-Q [ j ] = e C D F train-set (s c o r e [ j ] ) where score[ j] is score generated by method from high to low indicating the likelihood of the j-th variant to be a true variant.
Obviously, truncation errors occur by this method which depend on the chosen step size and the kinematic assumptions of the mechanical model.
Mr Johnson's version of that strategy was not the usual method, which depends on memory and discipline.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com