All methods were validated using both a random split validation and a temporal validation, with the latter being a more realistic benchmark of expected prospective execution.
The methods were validated based upon 2001 FDA method validation guidance.
The proposed methods were validated according to the ICH-guidelines for validation of the analytical procedures [20] in terms of the linearity, sensitivity, accuracy, specificity, repeatability and reproducibility.
While some assessment methods were validated for their respective study populations through pilot methods, validation for the population under study was not a consistent feature for all methods.
After Coakley lost and Wagner's methods were validated, the Democratic Party poured money into Wagner's department, which grew from 2 people to 15.
Four ICV estimation methods were validated through comparisons with the fully delineated ICVs.
The two methods were validated using a set of check points and were subsequently compared.
The accuracy of the design methods were validated against the test results.
The UHPSFC and UHPLC methods were validated based on the total error approach using accuracy profile.
Both optimized sample pretreatment methods were validated with the BCR reference material no.
In this study, quantitative microdialysis methods were validated in excised porcine skin experimental systems in vitro.
