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For example, numerous computational methods have been devised to predict potential protein-protein interactions, but high-throughput experimental methods typically exhibit a high false positive rate, precluding the development of a well-validated dataset.
As described above (and in accord with anecdotal experience), phylogeny-based methods typically exhibit high false negative rates, while simple BLAST-based homology detection methods exhibit high false positive rates.
Chromatographic methods typically exhibit better concentration detection limits, are not as sensitive to high-salinity matrices, and have more-established interfaces to selective detectors.
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Subsequently, the spatial learning ability of the animals was evaluated in the reference version of the Morris water maze, an established hippocampal-dependent task (see Materials and Methods) where aged animals typically exhibit impaired learning of the location of the hidden escape platform (Gallagher et al, 1993).
These new methods have a number of advantages but typically exhibit difficulties with linear superposition of waves.
Rating scales typically exhibit positive skew however small departures from normality do not preclude parametric methods.
Pathogens that evade adaptive immunity typically exhibit antigenic variation.
EWT solar cells typically exhibit rather low fill factors.
Current medical adhesives based on cyanoacrylates typically exhibit cellular toxicity.
Energy systems are shown to typically exhibit objective-wise uncertainties.
As a positive control we collected foragers, which typically exhibit strong circadian rhythms30,58.
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