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In addition to model-based methods, the program also implements bootstrap methodology.
For both methods, the program performs a series of analysis evaluation modification cycles: the design of the HFRP plate volume considered as the objective function is analyzed, the results are evaluated against specified design criteria, and the design is modified as necessary.
We needed to apply a boundary condition to the outlet; applying a standard "outlet" condition resulted in slower runtime and program warnings due to the methods the program uses to apply an outlet condition.
To investigate the phylogenetic relationships among species in the A. gambiae complex, we have used microsatellite polymorphism in 414 field-collected female mosquitoes with 42 markers covering the whole genome, and systematically analyzed the data genome-wide or regionally using three statistical methods: the program STRUCTURE, Principal Component Analysis and Correspondence Analysis.
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Using this optimization method, the program runs faster by a factor of almost one fifth.
The structures were solved by direct methods using the program SHELXS97 [17].
These inconsistencies could be due to methodological issues including different migraine assessment methods and the program of cognitive assessment.
Kinetics of βH reactions were analysed by using linear least-squares fitting methods with the program GraphPad ©Prism 5.0.
Algorithms 1 and 2 in Additional file 2 show how both methods of the program interact.
The BD rates were also estimated using fully automated methods with the program BadiRate (Librado et al. 2012) version 1.3.
The AH single crystal structure was solved by direct methods using the program package WinGX (SIR2004 and SHELXL97).
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