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In both BB and BRB methods, the expected animal location at intermediate times is assumed to slide along a straight line from one relocation to the next with a constant local speed, involving a homogenous movement process.
We revised this androdioecious model to numerically simulate the experimental transitions to selfing by accounting for females in the segregation of fog-2 genotypes (see Methods; the expected reproduction table under trioecy is presented in Additional file 1: Table S2).
This method is compared with two other similar methods: the Expected Conditional F-statistic method (ECF method) presented by Lai YL et al. [ 7] and the Detection of Altered Gene Associations method (DAGA method) proposed by Yoon SH et al. [ 9].
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In this method, the expected value of the objective function is evaluated using numerical approaches.
All the shown 21 phase volumes obtained from the gated CT scans were analysed as an additional verification of the phantom and CT analysis method: the expected sinusoidal-like curves were produced for all the settings.
Therefore we computed for each method the expected overlap using reshuffled data from 1000 permutations.
As shown in eqn (2a), before estimating Ne in the LD method, the expected contribution of sampling error is subtracted from the empirical.
For each method, the expected cases in a given month were defined by the previous 5 years of data and sequentially updated for each new observation year in the series.
Both methods reported the expected isoform abundances.
We adopted the setup that gave the highest correlations between the SI-based and HWE-based methods with the expected direction signs.
The vast majority of these account for known epistemic uncertainties, with methods optimizing the expected performance or finding solutions that achieve minimum performance requirements.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com