Sentence examples for methods the continual from inspiring English sources

For the heuristic optimization methods, the continual search is commonly necessary, and the system function call is required for each search.

Basically there are two approaches for guiding the number of patients enrolled at each dose level: algorithm-based methods such as the classical 3 + 3 and more recent model-based methods such as the different versions of the continual reassessment method [ 1- 3].

The last is the latest method and allows for the continual use of our centres.

Japanese physicians are not yet familiar with the methods underpinning continual collaboration with PCTs because this approach originated abroad, and some physicians harbour misconceptions about PCTs (e.g., that these units will not take any responsibility for patients).

Gold production continued to rise throughout the 20th century, partly because of the improvement in recovery methods and partly because of the continual growth and expansion of South Africa's gold-mining operations.

The traditional method (TM), also known as the 3 + 3 up-and-down design, and the continual reassessment method (CRM) are commonly used in Phase I oncology trials to identify the maximum tolerated dose (MTD).

The continual reassessment method (CRM) was first introduced by O'Quigley et al. [1990. Continual reassessment method: a practical design for Phase I clinical trials in cancer. Biometrics 46, 33 48].

The new design is compared to the continual reassessment method.

The continual reassessment method and its applications: a Bayesian methodology for phase I cancer clinical trials.

Practical modifications of the continual reassessment method for phase I cancer clinical trials.

Many clinicians often do not feel comfortable with the Continual Reassessment Method (CRM).