Sentence examples for methods that systematically from inspiring English sources

For instance, computational chemogenomic methods that systematically use phenotypic responses of both drug treatments and protein perturbations are widely used in predicting compound target interactions using both supervised and unsupervised approaches [ 6, 46].

The use of high-throughput techniques to generate large volumes of protein-protein interaction (PPI) data has increased the need for methods that systematically and automatically suggest functional relationships among proteins.

In particular, we applied an iterative decomposition method (see Methods) that systematically uncovered core networks with nodes having degrees of at least k.

To overcome such limitations, the present study introduces Wrap 'n' Shake (WnS), an atomic resolution method that systematically "wraps" the entire target into a monolayer of ligand molecules.

To address this problem, we have developed a computationally efficient ActiveGEnSeMBLE method that systematically predicts multiple conformations that are likely in the GPCR activation landscape, including multiple active- and inactive-state conformations.

We argue that the conventional procedures for risk factor validation could be enhanced with the addition of a supplementary method that systematically assesses diverse independent lines of evidence.

This leads to usually overestimate the latent trait level (and jointly underestimate item difficulties) producing negative bias for the v parameter except for the WORST method that systematically underestimates the latent trait level by only imputing negative responses.

In a recent article published in PLoS ONE, Yang and Agarwal [ 10] present a computational method that systematically explores novel potential applications of already marketed drugs in distinct therapeutic areas (for example, suggesting an antidiabetic effect for an anticonvulsant drug).

Thus, novel methods that can systematically identify motif modules in the entire non-coding regions around human genes are needed.

The two methods that have been systematically standardised are immunocytology (IC) targeting single tumour cells and ribonucleic acid (RNA -based RNA -basedanscreverse-polymerase chain reaction (RT–PCR).

The objective of this study is to describe a method that will systematically and efficiently obtain a model of computerized tomographic (CT) scanning factor levels, which returns optimized high quality CT images.