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(For the analytical performances of these methods, see Supplemental Material).
For additional details on " Materials and methods," see Supplemental Methods.
Pluripotent cells were cultured by standard methods (see Supplemental Information for details).
Finally, results were similar when we used standard regression methods (see Supplemental Material, Tables S6 S7).
For additional details on study design and methods, see Supplemental Material (http://www.ehponline.org/members/2008/10735/suppl.pdf).org/members/2008/10735/suppl.pdf
For selected strains, the antimicrobial drug resistance phenotype was analyzed by using conventional methods (see Supplemental Methods section at http://bigsdb.web.pasteur.fr/klebsiella/archives/Bialek_TechnicalAppendix.pdf).pdf
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RT-PCR analyses were simultaneously performed on mRNA preparation used for microarrays to validate the method (See Supplemental Data, Table S2).
A total of 6,711 proteins were identified at a 1% false discovery rate (FDR) as determined by the target-decoy search method (see supplemental materials: Text S1, Figures S2 and S3 for detailed explanation).
For a detailed description of the analytic method, see Supplemental Material, "LMM Analysis".
For a detailed description of the method, see Supplemental Material, "Bioactivation of Dust Samples" and Figure S3.
We also found the enrichment for proteins involved in HNF4α signaling using this alternative method (see Supplemental Material, Figure 2).
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