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Moreover, a comparative study regarding to methods' robustness, imperceptibility and algorithms' efficiency (time performance) is achieved.
Sensitivity and Monte Carlo analysis evaluate the methods robustness and illustrate the uncertainty of current LCA methods.
Complete references are in Additional file 2 and more extensive results are in Additional file 1, including data sources, average ages, statistical methods, robustness tests, and control variables.
The traditional steps of building gene trees (constructing multiple alignments, the choice and configuration of inference methods, robustness verification, etc).
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Method robustness was investigated using a Plackett Burman experimental design.
This strategy ensures that method robustness is built in during development.
To evaluate the HPLC method robustness, a few parameters were deliberately varied.
For evaluation of analytical method robustness, Plackett-Burman design was employed and for sample preparation method robustness Fractional Factorial design was used.
In addition, the platform AQbD method development strategy ensures method robustness is built in during development.
Quality-by-design based method development results in increased method robustness.
An experimental design was used during validation to evaluate method robustness.
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