However, many of these methods require time-consuming extraction and cleanup steps.
However, the materials used in radioactive label methods are expensive, and the methods require time-consuming steps to separate unreacted products.
Additionally, all of these methods require time-consuming tissue culture steps that are not compatible with high-throughput generation of mutants, and still can produce chimeric transformants that may not pass the trait on to the next generation.
Simple methods can be found with less accuracy, while accurate methods usually require time consuming analysis.
This approach has numerous advantages over the Bayesian method and it does not require time consuming analyses of population structure, as calculations are performed relatively fast [ 64].
These calculations require time consuming trigonometric operations.
However, to date the analysis of intracellular proliferation and yeast uptake by phagocytes has required time consuming methods, thus preventing high throughput screening or related experimental approaches.
The evaluation of fatigue properties of metallic materials with conventional methods requires time and cost consuming experiments.
However, current methods of spine analysis require time-consuming and labor-intensive manual spine identification in large image data sets.
Its calculation of means and correlations is instantaneous and furthermore its computing time does not increase a lot with the number of SNPs, contrary to all other methods based on multiple testing for SNPs that also require time-consuming methods to control the alpha risk (Churchill and Doerge, 1994).
However, such footprint assessment protocols remain poorly parameterized, especially those requiring time-consuming empirical methods [22].
