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Most of these methods require reliable estimations of higher hydrocarbons (i.e. C5+), which cannot be derived by conventional degassing methods due to inefficient liberation of higher hydrocarbons.
However, homology-based methods require reliable evolutionary information, for example, multiple sequence alignment constructed from enough number of protein sequences.
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Furthermore, the successful application of current methods requires reliable information about species distributions, which is not always available.
The WISN method requires reliable workload information to produce accurate results [ 8].
Regression-based methods require the reliable recording of additional EOG channels and are limited by the fact that the EOG is contaminated by brain activity which is removed as well.
Successful implementation of micromachined sensors in measurement instrumentation and interfacing between the micro- and macro-scale elements of the system require reliable methods for interconnection of these components.
To understand painted turtle adult age distributions, researchers require reliable methods.
Future clinical trials will require reliable and reproducible methods to subgroup clinical medulloblastoma samples in a fast way.
The successful introduction of anti-angiogenic therapies into cancer clinical trials will require reliable, non-invasive methods of assessing angiogenesis and its modification or inhibition in vivo [19].
In this context, a challenging issue still remains the full understanding of the temporal dynamics and anatomic distribution of (draining) LN involvement across the different phases of the disease, an objective that would require reliable and noninvasive methods of LN evaluation for serial and systemic analyses.
EM geophysical methods require accurate and reliable measurement of the electric field (E-field) and magnetic field (B-field) in order to characterize the subsurface, from the near surface down to a depth of several kilometers.
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