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New proposed design methods propose less conservative results comparing with existing works.
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The methods proposed are simpler, less time consuming and more sensitive than those previously published.
Therefore, the additional methods proposed potentially incurring less overhead compared to method 2 are explored in order to reach a good compromise, which improves the effectiveness of method 1 without adding a significant overhead in terms of the time needed for running a crawl.
From the early days of NMR spectroscopy it has been recognized that for some nuclei, in particular the proton, large gains in resolution could be achieved if the effects of homonuclear spin spin couplings could be suppressed, but for many years all the methods proposed proved more or less unsatisfactory.
The methods proposed in this work are computationally less expensive as compared to the flux correlation based approaches.
So many data compression methods are proposed, but less focus on the lossless compression.
The external fixation method proposed in this study requires less hospitalization time no major adjustment after application.
The methods of tissue fixation were entirely standard and in fact we had also done the less-ideal method proposed by the reviewer (immersion fixation of the entire brain) and the results were the same.
This is consistent with the more cluttered optimization landscape shown for a real iris and the fact that this landscape (see Fig. 4) deteriorates much less for the method proposed here.
However, under the two Bayesian methods, the proposed BLOR showed less bias than BLOR*, and this behavior is observed for all parameters and PO under study, except when the PO is 30% and for the parameter γ2.
Numerical examples show that the proposed methods are less conservative than existing ones.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com