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Thus, these methods produce statistically sound results, albeit under slightly different null hypotheses.
In order to be able to assess whether two different methods produce statistically significant differences in the results obtained we employ McNemar's test [38].
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We applied our method to two real data sets, and showed that it can produce statistically more significant gene functional modules than conventional clustering methods such as k-means and self-organizing maps, evaluated by a number of criteria.
Whereas in NOTCH1 and RELA gold standards it takes only 5-105-10%noise to make the results statistically indistinguishable from orientation by chance, in YEAST and ECOLI gold standards the methods can tolerate much higher proportions of noise and still produce statistically significant results.
It is also important to note that as a qualitative research method, Delphi studies do not, and are not intended to, produce statistically significant results.
We used the multiple imputation measurement error (Cole et al., 2006) method of transforming CSF Aβ42 into PIB PET units to produce statistically equivalent measures of Aβ load from either biomarker source (Weigand et al., 2010).
Response surface methodology (RS M is a statistical method used to determine the minimum number of experiments conducted to still produce statistically significant results (Wang et al. 2011).
The four prediction methods require a MSA to have a minimum of 10 sequences meeting this criterion to produce statistically significant results.
Pencina [ 4] discussed that even small NRI values (<0.01) might produce statistically significant p values and Pepe et al. [ 5] points out that valid methods for inference for the NRI do not exist.
Other comparisons did not produce statistically significant differences.
Both restricted models produce statistically significant E-R slopes.
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