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However, many of the current methods present substantial drawbacks which can limit their application and confound results.
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The point-radius method clearly fails on the first count and also likely will present substantial problems in terms of patient privacy.
These unknowns all present substantial threats.
Flaviviruses present substantial differences in their host range and transmissibility.
But the prevailing methods present unattractive trade-offs.
Silver's methods present a dilemma for television networks.
Both agreements present substantial differences and stem from unique circumstances.
Nevertheless, these methods present severe limitations.
The uncertainties involved in the methods presented in this study are substantial.
When ILS is present, gene trees can differ from each other and from the species tree, presenting substantial challenges to phylogeny estimation methods (Degnan and Rosenberg, 2009; Edwards, 2009).
Functional genomics using RNAi is a particularly attractive technique for genomic mapping and annotation in plants because many plants are polyploid, which presents substantial challenges for more traditional genetic engineering methods.
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