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Prediction of the subcellular location of the IRI-like peptides (see methods) predicted a signal peptide that targets the peptides to the secretory pathway present in all IRI-like peptides, except from LpIRI2.
However, while all methods predicted a SP in both DIA1 and DIA1R, some methods used had varying success in pin-pointing the exact cleavage site used to generate the mature protein.
Furthermore, concordant SP cleavage sites were predicted by all three methods for DIA1 proteins from 6 species, with very similar cleavage sites predicted for DIA1s from a further 11 species (i.e. where 2 of the 3 methods predicted a cleavage site aligning with the concordant site, and the remaining method predicted the adjacent amino acid as the cleavage site).
If more than seven methods predicted a residue to be helical, it was assigned as such.
Both methods predicted a 42 nt conserved site overlapping the CRP site predicted from the known consensus.
Our previous work [ 6, 7], using stochastic simulation and ordinary differential equation methods, predicted a dose-dependent P53, NFκB and CyclinE response curve to the increase of AKT and IKK.
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16 Many existing coiled coil prediction methods predict a continuous coiled coil and also are capable of reporting stutters and stammers.
These simple methods predict a win for Mr. Obama — but with a lot of hesitation, by about 1 percentage point in the national popular vote.
Straightforward thermodynamic analysis (see Methods) predicts a relationship of δ ΔG) and the maximum triple helix folding temperature T0+δT with the HSP47 dissociation constants at different sites on folded and unfolded procollagen chains, Eqs.
This opens the question of why model-fitting methods predict a threshold length from STR distributions.
Therefore, EFICAz makes an inference when one or more of the four component methods predict a particular enzyme function.
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